Delayed type hypersensitivity for penicillin in mice I. Induction and characterization of delayed type hypersensitivity for penicillin in mice.
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چکیده
منابع مشابه
Oral tolerance for delayed type hypersensitivity contribution of local and peripheral mechanisms
Oral tolerance is a physiological immune mechanism, which controls the outcome of deleterious hypersensitivity reactions to environmental antigens absorbed through the gastrointestinal tract, and maintains homeostasis. Using a mouse model of oral tolerance of delayed type hypersensitivity to contact allergens, i.e. haptens, we have examined the mechanisms involved in the induction of oral toler...
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The systemic injection of high doses of antigen into a preimmunized animal results in transient unresponsiveness of cell-mediated immune responses. This phenomenon is known as desensitization. Serum interleukin 2 (IL-2) activity was found transiently in desensitized mice at 3 h after the antigen challenge. These mice could not reveal antigen nonspecific delayed-type hypersensitivity (DTH) 1 d a...
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Delayed-type hypersensitivity (DTH) 1 is a T cell-mediated reaction resulting in a mononuclear cell-rich inf lammat ion and swelling that peak 24-48 h after local antigenic challenge. In spite of the extensive use of D T H to dissect regulatory (1), genetic (2), and molecular (3) aspects of in vivo T cell responses, little is known of factors that regulate the persistence o f these reactions. I...
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Delayed-type hypersensitive (DTH) response was evaluated in C3H/HeJ mice intestinally infected with Entamoeba histolytica. Infected and non-infected control mice were challenged with amoebic antigen on day 5, 10, 15, 20, 25, 30, 40, 50, and 60 post-infection. Maximum footpad swelling was observed after 24 hours of the challenge. The E. histolytica-infected mice exhibited a DTH response on day 5...
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Mice infected with A/England/939/69 X A/Puerto Rico/8/34 (Rec 31) influenza virus by aerosol develop significantly lower levels of delayed-type hypersensitivity (DTH) to A/Hong Kong/1/68 X A/Puerto Rico/8/34/ (X31) virus compared to uninfected mice. The suppression of DTH to the hemagglutinin appears to be mediated by suppressor T cells which carry Lyt-1 membrane antigen marker, and not by sy s...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1981
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.34.452